Chromosomal abnormalities quietly affect pregnancy preparation: How can IVF-PGT help avoid genetic issues?

2026-10-26 16:02:46，浏览量： 9次

Today, with the rapid development of society, late marriage and delayed childbearing have become a common trend. However, as people age, fertility issues have gradually become a challenge faced by more and more families. Chromosomal abnormalities, especially during pregnancy preparation, often silently affect the journey to pregnancy for many prospective parents.

 

Chromosomal abnormalities are one of the major causes of infertility. Human chromosomes are composed of DNA and proteins, responsible for organizing and transmitting genetic information. Under normal circumstances, our cells should contain 23 pairs of chromosomes to ensure the proper transmission of genetic material. However, due to errors during the natural process of meiosis, abnormalities in the number or structure of chromosomes are common. These abnormalities can cause numerical issues, such as chromosome gain or loss, or structural problems, such as deletions, duplications, or translocations.

 

During the preparation for pregnancy, early testing is particularly important if there is a risk of chromosomal abnormalities for both partners. These tests can detect issues early in pregnancy, ensuring the health of the fetus. For couples preparing for pregnancy, chromosomal karyotype analysis can help assess potential genetic risks, providing a basis for future reproduction.

 

Chromosomal abnormalities are not only a potential hidden danger in pregnancy screening but also directly affect a couple’s fertility. For women, poor ovarian development and poor egg quality are often closely related to chromosomal abnormalities. For men, the older the age, the higher the likelihood of sperm quality decline, and the increased risk of chromosomal abnormalities. Most seriously, these abnormalities not only affect the pregnancy process but may also be passed on to the next generation, putting the child at risk of genetic diseases.

 

Especially for couples preparing for pregnancy at an older age, the risks associated with chromosomal abnormalities are even more significant. Research shows that women over 35 have a significantly higher risk of chromosomal abnormalities during pregnancy. More worrying is that these embryos often experience early miscarriage, with chromosomal abnormalities being one of the leading causes of early miscarriage.

 

So, for prospective parents at risk of chromosomal abnormalities, how can they successfully conceive a healthy baby? Fortunately, with the advancement of medical technology, IVF-PGT (Preimplantation Genetic Diagnosis/Screening) offers these families a new option. Through preimplantation genetic diagnosis/screening, doctors can select healthy embryos and avoid the transmission of chromosomal abnormalities, significantly reducing the incidence of genetic diseases.

 

For older women, PGS technology is particularly important as it can prevent chromosomal abnormalities and miscarriage risks due to aging, improving the chances of a successful pregnancy. Dr. Nathan Zhang (Dr.Nathan zhang) established the IVF USA team, which has been engaged in overseas assisted reproduction consulting services for more than ten years, providing US egg freezing, US IVF, and third-party assisted reproduction services for people in need. IVF USA, which has been deeply engaged in the overseas assisted reproduction field for nearly 20 years, based on the diversification and personalization of reproductive needs, laid out the Mexican market early and became the agent in China for Power Fertility Center Mexico POWER Reproductive Center (POWER IVF). Currently Dr. Nathan Zhang’s business has expanded to Mexico IVF and egg freezing outside the US, Japan and Thailand IVF and egg freezing, as well as Taiwan, Hong Kong and other regions, With years of experience, IVF USA and Dr. Nathan Zhang can offer professional guidance and support to each couple, helping them take more confident steps on their journey to parenthood.